DynaCHIP

DynaCHIP is a suite of next gen biosensor platforms that exponentially accelerate mass spectrometry workflows, enable rapid insight into CPPs and CQAs for cell-based bioprocesses and provide real-time monitoring for feedback control across all of biomanufacturing.

DynaCHIP

The DynaCHIP is a simple benchtop device that is comprised of a direct sample interface, a benchtop control box and our proprietary microfluidic chip design. With a detachable interface to provide remote flexibility, the DynaCHIP directly interfaces with any Mass Spectrometer for a simple and fast direct-from-sample-to-analysis process.

1-Second Sample Prep
Micro-fabricated Mircofluidic Chip for Highly Repeatable Sample Prep
Drop-in Interface with any ESI Mass Spectrometer
Makes Mass Spec Simple to use for the General Practitioner

DynaCHIP Applications

Common Mass Spec Workflows

mAB Screening: Glycan Analysis, Conformation, etc.

High-Abundance Protein Removal (e.g., Albumin)

Rapid Cell Culture Media Analysis: Cytokines

Diagnostics, General Sample Prep

DynaMARK

The DynaMARK leverages the DynaCHIP platform to enable deeper insight into Advanced Therapy processes. This is achieved from layering our proprietary data science software module on top of the core rapid mass spectrometric analytics.  DynaMARK fills a crucial void in the Cell and Gene Therapy space.

ML Data Science Module
On-Demand Cell State Characterization
Dynamic Measurements of CPPs & CQAs
Real-Time Feedback Loop

DynaMARK Applications

Mass Spec for Advanced Therapies Workflows

On Demand Fingerprint of Cell State:
e.g., proliferation, confluence, differentiation, activation

Critical Process Parameters (CPPs) and Critical Quality Attributes (CQAs) Identification and Monitoring

Flexible Applications: iPSC, T-Cell, MSC process development

Biologics: conformation, glycan analysis, QC, etc.

DynaLOOP

The DynaLOOP is an in-line biosensor platform that leverages the DynaMARK platform to enable in-process monitoring and feedback control.

Continuous Monitoring and Feedback Control
Real-Time Cell-State Characterization
Bioreactor Agnostic Integration
Multi-Bioreactor Interface

DynaLOOP Applications

Biomanufacturing

Cell and Gene Therapies

Vaccines

Biologics

Tissue Engineered Medical Products

Pilot Partnership

We're currently working with Pharma Co's and Biotechs to accelerate their Mass Spec workflows, and with Advanced Therapies Developers to enable better cell-state characterization.

If we can help accelerate your Mass Spec workflow or help measure critical biomarkers and cell-state for your iPSC and MSC research, please reach out!