DynaCHIP + DynaMARK comprise a next gen biosensor platform that exponentially accelerates mass spectrometry workflows, enables rapid insight into CPPs and CQAs for cell-based bioprocesses and provides dynamic feedback control for biotech and biopharma workflows.
The DynaCHIP is a simple benchtop device that is comprised of a direct sample interface, a benchtop control box and our proprietary microfluidic chip design. With a detachable interface to provide remote flexibility, the DynaCHIP directly interfaces with any Mass Spectrometer for a simple and fast direct-from-sample-to-analysis process.
In “standard operation,” the device utilizes advanced microfluidics and a novel "active sample treatment" to separate, isolate and amplify critical biomolecules from complex biochemical samples in the following manner.
Load Chip
Inject Sample
Press Go
DynaMARK is a SaaS module that interfaces with the back end of any mass spec and leverages the DynaCHIP platform to enable deeper insights into Advanced Therapy processes. Its easy-to-use interface and advanced visualization tools empower clients to turn their mass spec data into valuable bioanalytic insight for biomarker discovery and beyond. DynaMARK fills a crucial void in the Cell and Gene Therapy space.
Yes. The DynaCHIP benchtop instrument and DynaMARK software module are designed to seamlessly interface with any mass spec instrument, providing an easy and efficient upgrade to your current workflows without the need for extensive new equipment.
Our platform, combining DynaCHIP and DynaMARK, is specifically designed for the dynamic nature of cell-based bioprocesses. It provides consistent, repeatable results with zero variance, capturing dynamic changes in bio-systems, thus ensuring high reliability and accuracy in data.
The Andson product platform is comprised of the following:
1. Instrument - Benchtop Control Box (BCB) + Remote Interface Module (RIM): DynaCHIP
2. Consumables - On-Chip Sample Prep: Microfluidic Chips
3. Software Module (SaaS) - On-Demand Bioanalytics: DynaMARK
Andson’s innovative platform simplifies, streamlines and optimizes mass spec workflows to unlock the potential of mass spectrometry for biotherapeutics discovery, development and manufacturing.
DynaCHIP's current microfluidic chips are designed to isolate large biochemicals (i.e., proteins and mAbs) from smaller MS interferents (salts, detergents, and metabolites). The true utility of DynaCHIP shines in intact-mass/top-down workflows with backend data analytics using associated large molecule modules in DynaMARK. Stay tuned for exciting new product offerings currently in development that will expand functionality to other biochemical classes and workflows.
Only a syringe, a syringe pump or an autosampler is all you'll need. The DynaCHIP handles the entire upstream workflow, from sample intake, to sample prep to ESI spray into your mass spec.
We're currently working with Biopharmaceutical leaders to accelerate their mass spec workflows, and with Advanced Therapies Developers to characterize and control the next generation of Advanced Therapies.
Reach out today to learn how we can accelerate your mass spec workflow!