The DynaCHIP technology is based upon a novel microfluidic chip design that exponentially accelerates sample clean up and conditioning for real-time electrospray ionization mass spectrometry (ESI-MS) analysis.
Ultra-High Throughput Sample-Prep Technology
Sample preparation is the current bottleneck for modern mass spectrometry. The DynaCHIP is a micro-mass exchanger utilizing tangential flow filtration for active sample conditioning in a flow-through configuration with a sample residence time of just 1-second.
The microfluidic chip is manufactured via advanced microfabrication that allows for scalable and reproducible production of the device. This ensures easy and repeatable sample prep every time.
Proprietary Engineered Fluidic System
Batch Microfabricated Fluidic Chip
Tunable Nanoporous Membrane
Broad Molecular Weight Coverage
Nano Sample Volumes
Repeatable, Single-Use Chip with Zero Variance
Tangential Flow Filtration + Microdialysis
Ultrafiltration of deleterious chemicals, e.g., salts
Infusing Proprietary Signal Enhancing Reagents
Expands Detection across Multiple Charge States
In-Line Sample to Mass Spec Analysis
Selectively Isolates Critical Large Weight molecules
High Throughput Mass Spec Analysis
1 sec
Extract Sample
1 sec
DynaCHIP Rapid Sample Prep
3 min
Plug and Play: Benchtop Device Mass Spec Interface
15 min
DynaMARK Bioanalytics: Feedback Control Cell-State Analysis
Drop-In Integration
DynaCHIP enables measurements of the biomolecules that matter most.